Bitte verwenden Sie diesen Link, um diese Publikation zu zitieren, oder auf sie als Internetquelle zu verweisen: https://hdl.handle.net/10419/163530 
Erscheinungsjahr: 
2016
Schriftenreihe/Nr.: 
ISER Working Paper Series No. 2016-04
Verlag: 
University of Essex, Institute for Social and Economic Research (ISER), Colchester
Zusammenfassung: 
EQ-5D is used in cost-e ectiveness studies underlying many important health policy decisions. It comprises a survey instrument generating a description of health states across ve domains, and a system of utility values for each state. The original 3-level version of EQ-5D is being replaced with a more sensitive 5-level version but little is known about the consequences of this change. We develop a multi-equation ordinal response model incorporating a copula specification with normal mixture marginals to analyse the joint responses to EQ- 5D-3L and EQ-5D-5L in a survey of people a ected by rheumatoid disease, and use it to generate mappings between the 3-level and 5-level descriptive systems. We find significant conflicts between the two, which would imply the reversal of an important conclusion in a real-world evaluation of drug therapies.
Schlagwörter: 
EQ-5D
ordinal response
copula
mixture models
rheumatoid arthritis
mapping
economic evaluation
JEL: 
C35
C83
D61
H51
I10
Dokumentart: 
Working Paper

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