Bitte verwenden Sie diesen Link, um diese Publikation zu zitieren, oder auf sie als Internetquelle zu verweisen: https://hdl.handle.net/10419/309892 
Erscheinungsjahr: 
2022
Quellenangabe: 
[Journal:] The European Journal of Health Economics [ISSN:] 1618-7601 [Volume:] 24 [Issue:] 8 [Publisher:] Springer [Place:] Berlin, Heidelberg [Year:] 2022 [Pages:] 1297-1307
Verlag: 
Springer, Berlin, Heidelberg
Zusammenfassung: 
AbstractBackgroundThe EQ-5D and the SF-6D are examples of commonly used generic preference-based instruments for assessing health-related quality of life (HRQoL). However, their suitability for mental disorders has been repeatedly questioned.ObjectiveTo assess the responsiveness and convergent validity of the EQ-5D-3L and SF-6D in patients with depressive symptoms.MethodsThe data analyzed were from cardiac patients with depressive symptoms and were collected as part of the SPIRR-CAD (Stepwise Psychotherapy Intervention for Reducing Risk in Coronary Artery Disease) trial. The EQ-5D-3L and SF-6D were compared with the HADS (Hospital Anxiety and Depression Scale) and PHQ-9 (Patient Health Questionnaire) as disease-specific instruments. Convergent validity was assessed using Spearman's rank correlation. Effect sizes were calculated and ROC analysis was performed to determine responsiveness.ResultsData from 566 patients were analysed. The SF-6D correlated considerably better with the disease-specific instruments (s 0.63–0.68) than the EQ-5D-3L (s 0.51–0.56). The internal responsiveness of the SF-6D was in the upper range of a small effect (ES: − 0.44 and − 0.47), while no effect could be determined for the EQ-5D-3L. Neither the SF-6D nor the EQ-5D-3L showed acceptable external responsiveness for classifying patients' depressive symptoms as improved or not improved. The ability to detect patients whose condition has deteriorated was only acceptable for the EQ-5D-3L.ConclusionOverall, both the convergent validity and responsiveness of the SF-6D are better than those of the EQ-5D-3L in patients with depressive symptoms. The SF-6D appears, therefore, more recommendable for use in studies to evaluate interventions for this population.
Schlagwörter: 
EQ-5D-3L
SF-6D
Mental disorder
Validity
Responsiveness
JEL: 
I100
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