Please use this identifier to cite or link to this item: https://hdl.handle.net/10419/86442 
Year of Publication: 
2005
Series/Report no.: 
Tinbergen Institute Discussion Paper No. 05-042/4
Publisher: 
Tinbergen Institute, Amsterdam and Rotterdam
Abstract: 
Response Surface Methodology (RSM) is a tool that was introduced in the early 50's by Box and Wilson (1951). It is a collection of mathematical and statistical techniques useful for the approximation and optimization of stochastic models. Applications of RSM can be found in e.g. chemical, engineering and clinical sciences. In this paper we are interested in finding the best settings for an automated RSM procedure when there is very little information about the stochastic objective function. We will present a framework of the RSM procedures for finding optimal solutions in the presence of noise. We emphasize the use of both stopping rules and restart procedures. Good stopping rules recognize when no further improvement is being made. Restarts are used to escape from non-optimal regions of the domain. We compare different versions of the RSM algorithms on a number of test functions, including a simulation model for cancer screening. The results show that co! nsiderable improvement is possible over the proposed settings in the existing literature.
Subjects: 
Response Surface Methodology
Simulation Optimization
JEL: 
C61
Document Type: 
Working Paper

Files in This Item:
File
Size
353.53 kB





Items in EconStor are protected by copyright, with all rights reserved, unless otherwise indicated.