Please use this identifier to cite or link to this item: https://hdl.handle.net/10419/77305 
Year of Publication: 
2000
Series/Report no.: 
Technical Report No. 2000,03
Publisher: 
Universität Dortmund, Sonderforschungsbereich 475 - Komplexitätsreduktion in Multivariaten Datenstrukturen, Dortmund
Abstract: 
A basic step in the risk assessment of potential carcinogens is the determination of toxicokinetic parameters. The present approach is part of a strategy to determine the processes of uptake, elimination, and metabolism of the gas ethylene, an important industrial chemical, which is classified in category 3 of carcinogenic substances in the German list of MAK- and BAT-values. This paper deals with the calibration, which is indispensable to determine the decline of atmospheric concentrations of ethylene within a broad range of initial concentrations applied in an inhalation experiment.
Subjects: 
Ethylene
ethylene oxide
calibration
population toxicokinetics
risk assessment
Document Type: 
Working Paper

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