Please use this identifier to cite or link to this item: http://hdl.handle.net/10419/77228
Authors: 
Brunnert, Marcus
Müller, Oliver
Urfer, Wolfgang
Year of Publication: 
2000
Series/Report no.: 
Technical Report, SFB 475: Komplexitätsreduktion in Multivariaten Datenstrukturen, Universität Dortmund 2000,06
Abstract: 
In this paper we describe the principles of polymerase chain reaction (PCR) and its expanding use in molecular genetic research and molecular medicine. A short introduction of exemplary applications of the PCR is connected with a discussion of the lack of PCR accuracy. We give a statistical model for the PCR and discuss estimation methods in order to quantify the lack of PCR accuracy.
Subjects: 
Polymerase chain reaction
lack of PCR accuracy
branching process
estimation of the mutation rate
Document Type: 
Working Paper

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