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Brunnert, Marcus
Müller, Oliver
Urfer, Wolfgang
Year of Publication: 
Series/Report no.: 
Technical Report, SFB 475: Komplexitätsreduktion in Multivariaten Datenstrukturen, Universität Dortmund 2000,06
In this paper we describe the principles of polymerase chain reaction (PCR) and its expanding use in molecular genetic research and molecular medicine. A short introduction of exemplary applications of the PCR is connected with a discussion of the lack of PCR accuracy. We give a statistical model for the PCR and discuss estimation methods in order to quantify the lack of PCR accuracy.
Polymerase chain reaction
lack of PCR accuracy
branching process
estimation of the mutation rate
Document Type: 
Working Paper

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