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Brunnert, Marcus
Thiele, Ralf
Mevissen, Heinz-Theodor
Urfer, Wolfgang
Year of Publication: 
Series/Report no.: 
Technical Report, SFB 475: Komplexitätsreduktion in Multivariaten Datenstrukturen, Universität Dortmund 2002,38
The structural analysis of proteins is fundamental to the analysis of protein functions. In this context, sequence-structure alignment methods are important among the different empirical methods. In order to assess the quality of sequence-structure alignments, a statistical method using a Bayesian approach proposed by Lathrop et al. (1998) will be presented. Finally, the results of a developed statistical analysis of scores of RDP(recursive dynamic programming)-sequence-structure alignments (Thiele et al., 1999) according to data of six proteins will be described.
statistically significant scores
Combined Bayesian approach and RDP-alignment
Document Type: 
Working Paper

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