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Emrich, Katharina
Wolfgang, Urfer
Year of Publication: 
Series/Report no.: 
Technical Report, SFB 475: Komplexitätsreduktion in Multivariaten Datenstrukturen, Universität Dortmund 1999,48
In this paper we present a new method for estimating genetic parameters of an F2- generation model. Using an iterative algorithm we derive explicit expressions for the Maximum Likelihood estimates of the additive and dominance effects. Finally we calculate the variance covariance matrix of our Maximum Likelihood estimates, which enables us to determine a confidence interval for the location of a quantitative trait locus.
molecular genetics
Maximum Likelihood estimation
EM and ECM algorithms
variance-and covariance matrix of Maximum Likelihood estimates
confidence intervals for genetic parameters
Document Type: 
Working Paper

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