This paper offers a specific analysis of speculation bubbles in the economic history of the world, and then tries to identify the causes and effects of the speculation bubble on the real estate market in the USA, which was the main cause of the subprime crisis. The first part of the paper aims at defining the phenomenon of economic fluctuations and speculation bubble and presenting the most popular theories of overinvestment, which emphasize the importance of speculation phenomenon. The next part of the article describes direct causes of subprime crisis. Special attention has been paid to the processes taking place on the real estate market in the USA in the past fifteen years. The final section of the paper is a synthesis of theorems by the economists of Austrian School and Hyman Minsky, and then confronting them with real processes in the US economy in recent years.