Please use this identifier to cite or link to this item: http://hdl.handle.net/10419/49320
Authors: 
Vardeman, Stephen B.
Wendelberger, Joanne R.
Wang, Lily
Year of Publication: 
2003
Series/Report no.: 
Technical Report // Universität Dortmund, SFB 475 Komplexitätsreduktion in Multivariaten Datenstrukturen 2003,38
Abstract: 
We consider problems of quantifying and monitoring accuracy and precision of measurement in mass spectrometry, particularly in contexts where there is unavoidable day-to-day/period-to-period changes in instrument sensitivity. First we consider the issue of estimating instrument sensitivity based on data from a typical calibration study. Simple method-of-moments methods, likelihood-based methods, and Bayes methods based on the one-way random effects model are illustrated. Then we consider subsequently assessing the precision of an estimate of a mole fraction of a gas of interest in an unknown. Finally, we turn to the problem of ongoing measurement process monitoring and illustrate appropriate set-up of Shewhart control charts in this application.
Document Type: 
Working Paper

Files in This Item:
File
Size
316.91 kB





Items in EconStor are protected by copyright, with all rights reserved, unless otherwise indicated.