The patient-centred approach is expanding in the Danish healthcare system. This approach strives to organize treatment and care so that it takes departure in the individual patient’s personal values, wishes and motivations. The intention behind the approach is to offer more effective and more ethical treatment and care. The patient-centred approach assigns to a great extent the responsibility for individuals’ state of health and improvement to the individual patient. But what challenges does the approach pose for the professionals who work with it? In this thesis, I seek to explore the organizational and managerial problematics that the patient-centred approach implies in a case from the vascular specialty in the Danish healthcare system. The research question that I explore in the thesis is: How is preventive capacity and responsibility built and distributed in patient-centred prevention practices?