Please use this identifier to cite or link to this item: http://hdl.handle.net/10419/163530
Authors: 
Hernandez-Alava, Monica
Pudney, Stephen
Year of Publication: 
2016
Series/Report no.: 
ISER Working Paper Series 2016-04
Abstract: 
EQ-5D is used in cost-e ectiveness studies underlying many important health policy decisions. It comprises a survey instrument generating a description of health states across ve domains, and a system of utility values for each state. The original 3-level version of EQ-5D is being replaced with a more sensitive 5-level version but little is known about the consequences of this change. We develop a multi-equation ordinal response model incorporating a copula specification with normal mixture marginals to analyse the joint responses to EQ- 5D-3L and EQ-5D-5L in a survey of people a ected by rheumatoid disease, and use it to generate mappings between the 3-level and 5-level descriptive systems. We find significant conflicts between the two, which would imply the reversal of an important conclusion in a real-world evaluation of drug therapies.
Subjects: 
EQ-5D
ordinal response
copula
mixture models
rheumatoid arthritis
mapping
economic evaluation
JEL: 
C35
C83
D61
H51
I10
Document Type: 
Working Paper

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