The literature has not sufficiently engaged in the emergence and expansion of the phenomenon of slave trade. This article estimates whether or not slave trade affects human trafficking using an Ordinary Least Squares (OLS) with standard errors that are consistent with heteroscedasticity. The paper also checks for the robustness of the OLS model. The findings of the paper reveal that the effect of slave trade on human trafficking is positive and statistically significant.The more one is exposed to the phenomenon of slave trade, the more human trafficking is important. The paper also deduces that developed countries that experienced slave trade record low level of human trafficking nowadays, while developing countries continue to record high level of human trafficking. Additionally, institutions werefound to be statistically very significant, and essential to be politically and socioeconomically consolidated and promoted, mainly in developing countries in order to alleviate the level of human trafficking.