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SSE/EFI Working Paper Series in Economics and Finance, EFI - The Economic Research Institute, Stockholm School of Economics >
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http://hdl.handle.net/10419/56229
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| Title: | | Costs and quality of life in multiple sclerosis: A cross-sectional observational study in the UK  |
| Authors: | | Kobelt, Gisela Lindgren, Peter Parkin, David Francis, David A. Johnson, Michael Bates, David Jönsson, Bengt |
| Issue Date: | | 2000 |
| Series/Report no.: | | SSE/EFI Working Paper Series in Economics and Finance 398 |
| Abstract: | | We performed a cross-sectional, bottom-up observational study of resource consumption and quality of life of patients with multiple sclerosis (MS) in the United Kingdom. Three centers participated in the study. Patients received a questionnaire either by mail or during a clinic visit, and a total of 619 patients returned the questionnaire (the answer rate being around 70%). Patients provided information on all resource consumption, medical and non-medical, work absence and informal care related to their MS. Disease scores (Expanded Disability Status Scale, EDSS) were available for a majority of patients from the study centers, and were assigned using a matrix of disease (mobility) descriptions and EDSS scores. Mean total cost per patient and year was 16'717 £. When this cost is extrapolated to an estimated patient population in the UK of 80'000, total costs to society are estimated at 1.34 billion £. Direct costs represented 28%, informal care accounted for 26% and indirect costs amounted to 46%. Of the direct costs, an estimated £ per patient or % of total costs are paid for by the NHS. Intangible costs were estimated at 5000 £ per patient and year. The mean age of the cohort was 44 years (disease onset 34), the mean utility measured with EQ-5D was 0.487 (0.919 to -0.594), and the mean EDSS score 5.1 (1.0 to 9.5). All costs (direct, informal care, indirect) increased with increasing EDSS scores, while utilities decreased. |
| Subjects: | | multiple sclerosis cost-of-illness quality of life EDSS utility |
| JEL: | | D61 H42 H51 H55 I18 |
| Document Type: | | Working Paper |
| Appears in Collections: | | SSE/EFI Working Paper Series in Economics and Finance, EFI - The Economic Research Institute, Stockholm School of Economics
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